Inhibiting Serotonin with Advanced Technologies

Updated: Jan 22

The term “biotechnology,” according to, simply means using a biological approach to solve problems and create innovative products. In medicine, this can sometimes translate to the development of specific drugs to help treat a range of diseases.

This article focuses on selective serotonin reuptake inhibitors (SSRIs), the research behind them, and the impact it has on treating mood disorders.

How do SSRIs work?

Selective serotonin reuptake inhibitors are the most commonly prescribed antidepressants. They have also shown to be useful to treat a wide range of disorders with few side effects.

SSRIs focus on the levels of serotonin, a neurotransmitter. By blocking the reabsorption of serotonin into neurons, they can increase the levels of serotonin in the brain. Ultimately, this changes the chemical makeup and the way neurons interact with each other. The buildup of serotonin allows messages to be sent correctly. This increase in serotonin can have many positive effects within an individual.

Developmental History

In the 1950s, there were few options to treat mood disorders at the source that did not have severe adverse effects. As a result, SSRIs were developed as alternative antidepressant medication that targeted only serotonin and did not affect other neurotransmitters. In the 1980’s, there was larger access to neuro and biotechnology that could help scientists analyze and understand the specific chemical components involved. In 1983, the first “prototype,” called zimelidine, was developed and marketed. Today, SSRIs are utilized in millions of treatments worldwide in a broad range of disorders.

Future Research

Medicine continues to evolve and change daily. SSRIs have developed greatly since when they were first discovered. Since zimelidine, 6 more SSRIs have been created, as recently as the early 21st century. The side effects from these medications have progressively become less severe as our understanding of them grows. Furthermore, treatment for many disorders has greatly affected SSRIs and continues to help people around the world. Research continues in many psychological institutions to apply SSRIs to other areas and further enhance and develop them for optimal use.


Selective serotonin reuptake inhibitors were engineered to rewire the chemical framework of one’s brain in order to produce serotonin. In the decades since their creation and discovery, they have been refined to achieve the best results with the fewest and least severe adverse effects. Millions of patients with a variety of disorders have been treated with them, and due to ongoing research, many more will be able to receive those same positive results.


Unwired India is a neurotech-startup that aims at integrating state-of-the-art research and developments in STEM, for catalyzing the transition of Neuroscience to Neurotechnology. We develop avant-garde non-invasive neurostimulation products used to solve some of the world’s most critical global issues and challenges. Our mission is to take cutting-edge brain research directly into the lives and homes of people, thereby fostering a unique culture of sustainable neuroscience and scientific literacy in India.

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A friendly reminder: We've done our research, but you should too! Check our sources against your own and always exercise sound judgment. 

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About the Author

Davinia Ibizugbe

Article and Video Coordiantor, The Hope Project (Texas, USA)

Davinia Ibizugbe is a Nigerian writer. She has planned her education around the hopes of becoming a future Neurosurgeon. Her interest in neurology developed early in her life. Davina has a passion for learning about neurological diseases and methods to combat them.

We appreciate each & every single one of you and thank you for helping us build a space where you can directly connect and collaborate with minds and hearts that are trying to revolutionise the future of our people and planet.


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